That's a great idea. I actually have an idea for an episode like that. WARNING: I GOT TOO CAUGHT UP WITH THIS LOL.
Because of the fact I got too into detail into my idea for the episode, I put it in a spoiler thingy. If you can't be bothered to read it or don't want to etc, here's a tl;dr
Big Mac used to talk too much and it ended up making him ignorant to the problems around it, therefore he can relate to this pony because this pony turns out to be scared to be judged and therefore whenever he tries to talk, it comes out rudely, the pony doesn't actually realize any of this, and ends up hurting his friends etc.