A ton of things, but I'll nail it down to three.
-The scene in the Iron Will episode where Fluttershy's just yelling at Pinkie and Rarity. Now, I don't care much for Rarity, but the look on Pinkie Pie's face when she was getting picked on... it was the only scene in MLP that made me feel bad for a character.
- Rarity's pretty sad, but Pinkie Pie... oh dear Pinkie Pie...
-This was back in December while I was in Ethiopia. When we went to go visit a small village that my mother's great great parents founded. It was the most rural place on the planet, and everyone was happy and content living their lives knowing that they only needed the clothing on their backs, Jesus and the Lord, and the land to live happily. The saddest part was that the said village was the burial place of my mom's parents. Seeing her cry, especially when being told that the village needs money in order to be kept in tact (for some odd reason, not sure), hit me hard considering I never met my grandmother (and only meeting my grandfather once).
-Again, another story from my time in Ethiopia. We were getting ready to leave; on our way to the airport, and seeing my dad's mother's sad look on her face (she's been meaning to visit us in Canada, but because her Visa got screwed up by my uncle she can''t) made me feel REALLY sad. But the worst part was my dad's concern for someone we refered to as Ababyea (rough translation; in Amharic in generally means father, but in this case it was his nickname - translated, "Big Daddy"). He's basically blind and old and somewhat sick, and when he went to visit him, my dad came and when he saw Ababyea in bed he thought he was dead. It shocked him and I felt really crap looking at my dad who cared a lot for him. It turns out he was sleeping, so it was all good. The final bit about this story was that about a month ago, Ababyea had to go into surgery, and because Ethiopian Healthcare (or African Healthcare in general) is horrible, the doctor's fucked up and (from what I remember) he'd become permanently blind. Again, my dad told me this after speaking with his aunt over the phone, and we both just kinda felt sad. Only difference is he was able to keep it hidden from us (which pissed me off for some reason, considering that while he's not one to show a lot of sad emotion this hit him hard in the gut) while I just cursed under my breath for about 15 minutes. He's expected to live a few more years, 5 or more hopefully.
This is the only story I've told that almost made me tear up, despite it not involving me but moreso my dad. And I apologize for the long post.