I draw it when:
1. Anti-Bronies have to be extremely stupid, immature, and then an attention whore who brings in more hate.
2. When fellow Bronies are being bullied or trolled, I'll come in with my favorite weapon, common sense.
3. Finally, when something obviously not related to Bronies creates a huge uproar (ex, Meet the Pyro, nothing MLP related).
If all else fails, just punch them straight in the face ignore them or say, seriously? Gotta be that immature?
(also can somebody link me this video of this guy's artwork being destroyed?)