in summer of 2012, I tested my ability to stay up for as long as I could... I made it to 72 hours before I gave up, and it was terrible after the first day... As far as I can tell, the longer your awake, your brain starts to stop processing thoughts so that you can keep your vitals going longer. I had to keep consuming products, and keeping my face wet to keep me going... overall... Might do it again, far in the future...