Thank you for asking!!
Personally, I wouldn't tag these things with "What is wrong with you?", but I'd say that these things are just slight disabilities, nothing more.
Well, on my side of things, the only problem I have is being diagnosed with attention deficiency disorder.
The only problems it causes are the fact that I can't study as well as somepony else, and that I get this 'blank' in my mind every now and then.
Further on, it's been proven that people (adults or kids) who have ADD/ADHD are usually smarter than your average Joe, no offence to those here reading.
Then there's the chance that my future wife can bare a baby with downs-syndrome. My younger sister's sub-class of downs-syndrome is the one that runs in the family
But then again, downs-syndrome children are the most darling angels you can find!!
Thanks for your time!!!!
(due to immoral nature and scathing of people on the internet, I won't post a picture of a downs-syndrome child)