Gaming, anime, 3DS, PS3/4, Ipad, Steam, Team Fortress 2, MLP (OBVIOUSLY), earning achievements, merchandise of things I like, Adventure Games, I hate COD, Legend of Zelda, Free games, Twitch.tv, YouTube, Markiplier, Jacksepticeye, Doctor Who, Films, Anime Parody Dubs, everything else that I like
On your profile: Edit my Profile -> Notification Options; under 'status updates', remove the tick from 'Notify me when one of my friends updates their status'. I also keep turned off 'Notify me of replies to status updates I have replied to' =)
That's the only option, I'm afraid, aside from turning them on or off for good. =/ Though I'd still recommend you turn off 'Notify me of replies to status updates I have replied to', if there's often long conversations in status updates you comment on =)