Spike in Ori and the Will of the Wisps is one of the most satisfying weapons I've ever used in any game.
You dash into the air in a random direction, which can be used to dodge an attack, then a light spear slowly materializes in your hand. You hang in the air for a moment, giving you some time to choose the target, before launching the spear. It aims automatically and flies crazy fast, making it hard for you to miss.
That moment in the air before you throw, the speed, and the shockwave it creates on impact makes it feel incredibly powerful. If you focus on this weapon alone, you destroy all regular enemies in one hit and gain energy faster than you can use it on spears.