What would have happened if Twilight was the Mainpulator, not Cozy?

[saum22 6]

Here's the scenario I'm entailing. Twilight does not understand love in the conventional way, understanding as a grade on a test or something. (in this AU of sorts, that is.) This, causes after Twilight loses her teacher, the main proponent of love, for her to go into a depression. This causes Twilight to lash out at her friends, which makes her lose them, permanently. She goes mad after a few weeks, and becomes a major anti-harmonic force in equestria. 

This is near impossible in the cannon, but what do you think would happen?

[Emerald Heart 24,583]

Write a fanfiction about it and then we'll find out

[Misty Shadow 7,084]

This would...work much better for a writing help topic.  That would have never happened in the show because Twilight was intended to always be good and Cozy Glow was written as never actually being good. 

[BornAgainBrony 2,395]

Sounds like a Party of One sequel, just with Twilight instead of Pinkie?

[Light Blade 8,658]

With my personal beliefs, thought about this might corrupt and ultimately break me on substantial number of layers.