Technology:
My computer
My smartphone
My Nintendo Switch
The Internet
Television
Modern Medicine
Food:
I'm a true, dyed-in-the-wool, carnivore. So not being able to eat meat would really suck.
I love sweets, but I don't think my blood glucose levels would appreciate me eating Pinkie's sweets 24/7.
Family and Friends:
I'm sure I wouldn't be permitted to bring anyone along with me, so I'd become very lonely very fast.
Even after making friends with the ponies, I'd still want human contact.
Living in a Civilization built by humans, for humans:
Our civilization was built with our needs in mind. We have technology and modernity. Moving to Equestria, where technology is either primitive and supplemented by magic, or just non-existent, would be like going back in time to live in Medieval Europe, only with some modern touches.