Here's a smattering of them including only 1 from any particular franchise/source and in no particular order (there are dozens more I could name...)
John Locke
Gollum/Sméagol
Roy Batty
Paul Bäumer
Ellie Sattler
George Bailey
Fred C. Dobbs
Captain Steven Hiller
Juror 8 (and the other 11 too)
Mat Cauthon
Doc Brown
Scully & Mulder