The instinctive reaction is, of course, "No. Commit seppuku for even thinking it," but as always, the real response should be, "Can they do it well?" If it was well-written, well-acted, the animation didn't verge into Uncanny Valley (no CGI MLP pony I've seen so far has convinced me that this is possible) and there was an interesting and not contrived reason for them to be there ... yeah, it could just about work.